ea0007p42 | Diabetes, metabolism and cardiovascular | BES2004
Le Roux C
, Aylwin S
, Batterham R
, Borg C
, Wynne K
, Hunt C
, Coyle F
, Ghatei M
, Patel A
, Bloom S
Background: The gut hormone PYY3-36 (PYY) is released into the circulation after eating and physiologically inhibits food intake. Obese and lean subjects are equally sensitive to this effect, however fasting levels of PYY are reduced in obese subjects.Methods: We investigated the postprandial PYY response and satiety response using a visual analogue scale (VAS) to 6 test meals of increasing calorie content in 20 lean and 20 obese subjects. We also infuse...